Pyrilutamide solution in a propylene glycol and ethanol vehicle.
Concentration: 0.5% (5 mg/ml)
Size: 60 ml.
Purity of Raw Material: >99% pure. Every batch of Pyrilutamide, also called KX-826, is tested and confirmed by a 3rd party prior to usage.
Product comes with a calibrated dropper.
PyriPure is for research purpose only. Not for human consumption.
How do you test the purity of the product?
The raw material pyrilutamide (aka, KX-826) used in PyriPure was confirmed to be >99% pure by a professional testing lab. See reports here.
What is pyrilutamide?
KX-826, also known as Pyrilutamide or Pyri, is a new chemical developed by Suzhou Kintor Pharmaceuticals, a Chinese biotechnology company focusing on androgen receptor-related disease areas without effective treatments. These include conditions such as prostate, breast, and liver cancer as well as hair loss. Pyrilutamide is undergoing Phase II and III trials in China and the United States. Its structure is shown below in comparison to that of RU58841. As you cans see, they have very similar structures. The different parts are highlighted by red bonds.
How should the product be stored?
The 0.5% pyrilutamide solution is in an air and light tight bottle. The bottle should be stored in a cool environment such as a fridge.
How does pyrilutamide work to treat hair loss?
Pyrilutamide is a non-steroidal anti-androgen (NSAA). NSAAs work by blocking testosterone and DHT from binding with the androgen receptor in the follicle. This is different from GT20029, another compound developed by Suzhou Kintor Pharmaceuticals for the treatment of hair loss and acne. GT20029 (AR-PROTAC) works by degrading androgen receptors. DHT is the key androgen that causes hairs to thin. In the scalp, testosterone is converted into Dihydrotestosterone (DHT) by an enzyme called 5-alpha reductase. DHT strongly binds to hormone receptors in the hair follicle and activates genes responsible for the shortening of the growth phase. As this process is replicated over the scalp, hair coverage thins out usually over the crown, temples, and frontal areas. Pyrilutamide is an antagonist of the androgen receptor (AR). It binds to hair folicle AR to prevent DHT from binding to it.
